Dr White

Chronic kidney disease has a higher mortality rate than liver cancer

By Dr White

 

Liver cancer is a disease that many people are afraid to talk about. However, there is a disease that affects one out of ten people and has a higher mortality rate than liver cancer, but many people have never heard of it, which is

Chronic kidney disease

Over the past 30 years, the mortality rate for chronic kidney disease has increased to the point where it has surpassed liver cancer as the 11th deadliest disease. The number of deaths has also doubled.

Chronic kidney disease has little discomfort at the beginning, but the kidneys gradually break down unknowingly, and by the time the symptoms appear, they are often advanced, either waiting for a donor kidney, matching and surgery; or continuously doing dialysis, unable to get off the machine for the rest of their lives.

Unable to travel, physical pain, mental exhaustion and high costs.

You may be thinking that chronic kidney disease is far away from you.

No, it is all around you and me, but many of us never realize it.

In China, the prevalence of chronic kidney disease is about 10.8%, which means that about 1 in 10 people have chronic kidney disease.

With so many patients, where are they? Who are at higher risk?

Two special groups of people need to be mentioned here.

Hypertension, diabetes patients

Hypertension and diabetes are closely related to kidney health, they are not only more prone to kidney nephropathy, chronic kidney disease will also aggravate hypertension and diabetes, and under the vicious cycle, eventually lead to more serious systemic problems.

When it comes to the relationship between high blood pressure, diabetes and kidney, we must first introduce the daily work of kidney - "blood cleansing".

Every day, human blood circulates throughout the body 40-50 times, and all kinds of metabolic substances will take the "blood express" to the kidneys to complete filtration and purification. What is useful remains and continues to circulate, while what is useless is excreted as urine.

There are many "glomeruli" in the kidneys for blood filtration, which are made up of abundant capillaries. High blood pressure and blood sugar can damage the blood vessels.


Image credits：https://www.freseniuskidneycare.com/kidney-disease/how-kidneys-work

Long-term and continuous high blood pressure will lead to increased pressure in the blood vessels in the kidney. Under high pressure, the blood vessels rupture and harden, and the glomeruli gradually become fibrotic and atrophied, and the filtration network is damaged and cannot work properly.                       

As more and more glomeruli "die", kidney function gradually malfunctions and fails, and eventually uremia occurs.

The mechanism of damage to the kidneys in diabetes is complex and can be simply understood as the kidneys are overworked (hyperfiltration) in order to be able to filter out more sugar than the basal workload, which eventually leads to serious consequences.

Chronic kidney disease Can also aggravate hypertension, diabetes

When kidney damage occurs, the most immediate consequence is that the blood cannot be completely 'cleaned' anymore.

Excess water and sodium cannot be excreted in a timely manner and collect in the blood vessels, causing them to be under more pressure. Under sustained hypertension, the inner walls of the blood vessels in the kidney thicken and the vascular channels become narrow, further increasing the pressure on the blood flow. 

In addition, abnormal renal function may also stimulate hormones such as angiotensin to come on board, which can also affect blood pressure to some extent.

Hypertension and chronic kidney disease form a vicious circle that affects each other. According to the American Health and Nutrition Survey, 50.9% of people with chronic kidney disease have hypertension.

Chronic kidney disease can also trigger and exacerbate diabetes. In a mouse experiment, when kidney problems occur, urea that is not cleared in time causes impaired insulin release and abnormal blood sugar.

In other words, once a patient with hypertension and diabetes, develops kidney problems, the dangers of the disease are superimposed and the progression is likely to be more severe.

Chronic kidney disease continues to progress Systemic multi-organ discomfort will occur

Chronic kidney disease is irreversible, damaged to a certain extent, the kidneys will not be able to complete the work of filtration, a large number of substances in the blood can not be metabolized, a variety of poisoning, metabolic disorders appear - uremia.

Of all the organs, the heart, which is closely related to the blood, bears the brunt.

The morbidity and mortality of cardiovascular disease in patients with chronic kidney disease is at least five times higher than in the general population of the same age.

Other organs are also dependent on blood and can also be affected by chronic kidney disease.

What is more dangerous is that early kidney lesions have no symptoms, no pain, no swelling of the bag, and no functional abnormalities until they completely collapse.

Remind all hypertensive and diabetic patients that they must be sure to control their blood pressure and blood sugar.

In addition, urine test can effectively detect kidney abnormalities. Annual physical examination, don't feel that you are "quite healthy" and avoid it.

If any of your family members also have diabetes and hypertension, always remember to remind them.

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